Celgene Associate Scientist, Next Generation Sequencing in San Diego, California

Description

Celgene is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health. We value our passion for patients, quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries - and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture.

Summary/Scope

The Epigenetics Center of Excellence at Celgene is seeking a highly motivated and dynamic individual to join the group. He/she will support drug discovery projects focused on epigenetic targets, primarily in oncology. Specifically, the candidate will prepare libraries for next generation sequencing (NGS), operate NGS equipment, and assist in performing assays including Whole Genome Sequencing (WGS), Whole Genome Bisulfite Sequencing (WGBS), ChIP-seq, ATAC-seq, mRNA-seq, total RNA-seq, and single cell RNA-seq.

Responsibilities will include, but are not limited to, the following:

  • Independently operate and maintain NGS equipment.

  • Prepare libraries for sequencing studies.

  • Develop, trouble-shoot, and optimize sequencing protocols.

  • Assist in the design and execution of WGS, WGBS, ChIP-seq, ATAC-seq, mRNA-seq, total RNA-seq, and single cell RNA-seq experiments.

  • Accurately maintain written reports and organize data.

  • Present projects in team, department, and project review meetings.

  • Independently review current literature pertaining to NGS technology, oncology, epigenetics, and related assays.

Qualifications

Skills/Knowledge Required:

  • Bachelor’s degree in a scientific discipline with at least 6 years work experience or Master’s degree with at least 4 years work experience.

  • In-depth knowledge of current NGS technology.

  • Experience in library preparation.

  • Experience in operating and maintaining NGS equipment (Illumina preferred).

  • Experience in molecular and cell biology techniques including real time PCR, WGS, WGBS, ChIP-seq, ATAC-seq, mRNA-seq, total RNA-seq, and single cell RNA-seq is a plus.

  • Highly motivated, capable of multitasking, intense attention to detail, and innovative.

  • Excellent time management and organizational skills, strong written and oral communication skills.

Celgene is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.

Celgene complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Celgene in the U.S.

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BIO-US

Associate Scientist, Next Generation Sequencing

Location: San Diego, CA, US

Job ID: 17001720