Celgene Associate Bioengineer II in Summit, New Jersey

Description

Celgene is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health. We value our passion for patients, ​quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries, and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture.

DEPARTMENT

Process Engineering and Innovation, CAR T Manufacturing and Technology

PREREQUISITES

B.S. or M.S. in Biochemical, Chemical, or Biomedical Engineering or Biology or related discipline

Summary:

Provide technical and empirical support for the change control and innovation of cellular immunotherapies. Design, perform, and interpret experiments, with minimal supervision, to enable process engineering changes. Interface with Process Development and Analytical laboratories and/or participate in technical transfers to commercial sites and contract service providers.

Responsibilities will include, but are not limited to, the following:

  • With minimal operational supervision, plan and execute/implement cellular process engineering studies on one or more of the following areas: cell culture, cell harvesting, immuno-selection, tissue processing, cryopreservation, phenotyping, etc.

  • Design well-controlled experiments, perform data analysis, and summarize empirical results, with moderate technical/scientific supervision and feedback. Present results within project team and departmental technical reviews.

  • Support the development, optimization and validation of CAR-T manufacturing processes.

  • Qualify/transfer process methodology to/from GMP laboratories.

  • Adhere to all relevant compliance requirements.

  • As appropriate, interact with Development and Manufacturing teams to ensure efficient process transfer

  • Organize, record and maintain experimental data

  • Ensure proper operation and perform routine maintenance of all laboratory equipment

  • Assist other staff to complete all laboratory tasks as necessary

  • Maintain a clean and safe work environment in accordance with policies/procedures and OSHA safe practices

Skills/Knowledge Required:

  • B.S. in Biochemical, Chemical, or Biomedical Engineering or Biology related discipline with 1 - 3 years of relevant experience or M.S. with 0-2 years of relevant experience

  • Must have excellent organization skills and ability to handle multiple tasks

  • Highly motivated, willingness to acquire new skills and ability to work with minimal supervision

  • Must have strong engineering or scientific knowledge appropriate for bioprocess development

  • Experience in mammalian cell culture and aseptic technique is advantageous

  • Experience working in a GMP environment is advantageous

  • Excellent verbal and written communication skills

  • Must be proficient in Microsoft Word, Excel

#POST-LI

Celgene is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Celgene complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Celgene in the U.S.COMMITTED TO IMPROVING THE LIVES OF PATIENTS WORLDWIDE

At Celgene, we seek to deliver truly innovative and life-changing drugs for our patients. Our vision as a company is to build a major global biopharmaceutical corporation while focusing on the discovery, the development, and the commercialization of products for the treatment of cancer and other severe, immune, inflammatory conditions.

“At Celgene, we seek to deliver truly innovative and life-changing drugs for our patients.”

There are more than 300 clinical trials at major medical centers using compounds from Celgene. Investigational compounds are being studied for patients with incurable hematological and solid tumor cancers, including multiple myeloma, myelodysplastic syndromes, chronic lymphocytic leukemia (CLL), non-Hodgkin’s lymphoma (NHL), triple-negative breast cancer and pancreatic cancer. As committed as we are to clinical accomplishment, we are equally committed to patient support, which is a guiding principle at Celgene. We believe all who can benefit from our discoveries should have the opportunity to do so. Celgene puts patients first with industry-leading programs that provide information, support and access to our innovative therapies.