Celgene Associate Scientist / Bioengineer II in Warren, New Jersey

Description

Celgene is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health. We value our passion for patients, ​quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries, and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture.

Associate Scientist / Bioengineer IIWarren, NJ

SUPERVISOR

Senior Bioengineer

DEPARTMENT

Cellular Process Development

PREREQUISITES

B.S. or M.S. in Biochemical, Chemical, or Biomedical Engineering or Cell Biology/Immunology or related discipline

Summary:

Support deviations, process changes, and other GMP manufacturing activities as well as participate in process transfers and troubleshooting. Design, perform, and interpret experiments, with little supervision, focused on appropriate goals. Ensure smooth day-to-day operation of the cell culture laboratory and communicate with collaborators.

Responsibilities will include, but are not limited to, the following:

  • Assist with deviations and troubleshooting activities

  • Support manufacturing and QA by answering questions, clarifying intent of procedures, and solving problems

  • Review batch documentation, extract relevant data, and communicate findings

  • Assist in the development, updating, and review of procedures and executed records

  • Provide SME support in training of manufacturing and QA personnel as well as tech transfers

  • Interact with other CMC teams including Operations, QA, Development, and Regulatory

  • With minimal supervision, design and execute/implement cellular process development, characterization, and optimization studies on one or more of the following areas: cell culture, cell harvesting, immuno-selection, tissue processing, cryopreservation, phenotyping, transduction, cell delivery, infusion, etc.

  • Design well-controlled experiments, perform data analysis, and summarize empirical results, with moderate technical/scientific supervision and feedback

  • Manage inputs in real-time into databases

  • Applying knowledge of statistics and mathematical modeling of process development and clinical manufacturing data

  • Support process changes and implementation by routing change requests and rewriting procedures and executed records

  • Ensure proper operation and perform routine maintenance of all laboratory equipment

  • Assist other staff to complete all laboratory tasks as necessary

  • Maintain a safe work environment in accordance with policies/procedures/regulations

Skills/Knowledge Required:

  • B.S. in Biochemical, Chemical, or Biomedical Engineering or Cell Biology/Immunology related discipline with preferred 3-6 years of relevant experience or M.S. with 1-3 years of relevant experience

  • Must have excellent organization skills and ability to handle multiple tasks

  • Highly motivated, willingness to acquire new skills and ability to work with minimal operational supervision

  • Must have engineering or scientific knowledge appropriate for cellular process development

  • Must be competent and confident in mammalian cell culture and aseptic technique

  • Experience working in or supporting a regulated environment would be advantageous

  • Excellent verbal and written communication skills

  • Must be proficient in statistical data processing software such as JMP, Minitab, or Excel

  • Ability to review, interpret, and disseminate relevant developments in the literature

Celgene is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Celgene complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Celgene in the U.S.COMMITTED TO IMPROVING THE LIVES OF PATIENTS WORLDWIDE

At Celgene, we seek to deliver truly innovative and life-changing drugs for our patients. Our vision as a company is to build a major global biopharmaceutical corporation while focusing on the discovery, the development, and the commercialization of products for the treatment of cancer and other severe, immune, inflammatory conditions.

“At Celgene, we seek to deliver truly innovative and life-changing drugs for our patients.”

There are more than 300 clinical trials at major medical centers using compounds from Celgene. Investigational compounds are being studied for patients with incurable hematological and solid tumor cancers, including multiple myeloma, myelodysplastic syndromes, chronic lymphocytic leukemia (CLL), non-Hodgkin’s lymphoma (NHL), triple-negative breast cancer and pancreatic cancer. As committed as we are to clinical accomplishment, we are equally committed to patient support, which is a guiding principle at Celgene. We believe all who can benefit from our discoveries should have the opportunity to do so. Celgene puts patients first with industry-leading programs that provide information, support and access to our innovative therapies.